Hormone Replacement Therapy for Men: The Facts Behind the Headlines
Hormone replacement therapy (HRT) for men—particularly testosterone replacement therapy (TRT)—has drawn increasing interest in recent years. While the topic often garners attention in both medical forums and the media, the treatment isn’t suitable for every man and requires careful clinical assessment.
Who Benefits from HRT?
HRT is primarily recommended for men with clinically confirmed testosterone deficiency (hypogonadism), typically identified by:
Consistently low testosterone levels on laboratory tests
Symptoms consistent with low testosterone
A clear medical cause for hormone insufficiency
Despite popular claims, HRT is not a “fountain of youth” or a universal solution for ageing. It’s a targeted medical therapy.
Evidence-Based Benefits
In appropriately selected patients, TRT has shown measurable benefits:
Body composition: Increased lean muscle and reduced fat
Energy: Improved vitality and reduced fatigue
Cognition: Some evidence of enhanced focus and memory
Bone health: Strengthened bones and lower fracture risk
Sexual function: Enhanced libido and erectile function
Understanding the Risks
As with any medical treatment, HRT comes with potential risks:
Cardiovascular health: Possible increased risk in some individuals
Polycythaemia: Elevated red blood cells, requiring regular checks
Prostate monitoring: Ongoing review needed, though cancer risk appears low
Fertility: Possible suppression of sperm production
Sleep apnoea: May worsen in certain cases
Why Supervision Matters
Effective HRT requires:
Thorough clinical evaluation
Diagnostic testing before starting treatment
Regular monitoring and follow-up
Tailored dosing
Ongoing assessment of risks and benefits
Dr Crespo’s Thoughts
Testosterone therapy can offer real benefits for men with a genuine deficiency. It’s not a shortcut to feeling younger—it’s a medical decision. If you're experiencing symptoms, speak with a qualified healthcare professional. Avoid self-diagnosis or unregulated supplements. A thoughtful, evidence-based approach is always the safest path.
